MYC, Mouse, Clone: IMD-3, Abnova™

Catalog No.	Quantity
89-110-434	100 μg

Catalog No. 89-110-434 Supplier Abnova Corporation Supplier No. MAB1446

Description

Mouse monoclonal antibody raised against synthetic peptide of MYC.

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]

Specifications

• Antigen: MYC
• Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: 9E10
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of MYC.
• Dilution: Western Blot (4 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (8 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)
• Gene: MYC
• Gene Alias: bHLHe39/c-Myc
• Gene Symbols: MYC
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to human MYC.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4609
• Target Species: Human
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1