NEFH, Mouse, Clone: RT-97, Abnova™

Mouse monoclonal antibody raised against NEFH.

Supplier:  Abnova Corporation MAB11229

Catalog No. 89-109-399

Description

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq

Specifications

• Antigen: NEFH
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:400) The optimal working dilution should be determined by the end user.
• Gene: NEFH
• Gene Symbols: NEFH
• Immunogen: The Triton-X 100 insoluble protein fraction from rat brain.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Clone: RT-97
• Description: Mouse monoclonal antibody raised against NEFH.
• Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
• Gene Alias: NFH
• Host Species: Mouse
• Purification Method: Protein G affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4744
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ