NF1, Mouse, Clone: McNFn27a, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of NF1.

Supplier:  Abnova Corporation MAB2305

Catalog No. 89-110-919

Description

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq

Specifications

• Antigen: NF1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (2-5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: NF1
• Gene Symbols: NF1
• Immunogen: A synthetic peptide corresponding to amino acids 27-41 of human NF1.
• Regulatory Status: RUO
• Gene ID (Entrez): 4763
• Target Species: Guinea Pig, Human, Mouse, Rat
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: McNFn27a
• Description: Mouse monoclonal antibody raised against synthetic peptide of NF1.
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: DKFZp686J1293/FLJ21220/NFNS/VRNF/WSS
• Host Species: Mouse
• Quantity: 200 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to full-length or truncated forms of neurofibromin.
• Content And Storage: Store at 4°C for short term. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ