NQO1, Mouse, Clone: 4D12, Abnova™

Catalog No.	Quantity
89-109-039	100 μL

Catalog No. 89-109-039 Supplier Abnova Corporation Supplier No. MAB10835

Description

Mouse monoclonal antibody raised against partial recombinant NQO1.

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Specifications

• Antigen: NQO1
• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 4D12
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant NQO1.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: NQO1
• Gene Alias: DHQU/DIA4/DTD/NMOR1/NMORI/QR1
• Gene Symbols: NQO1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human NQO1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1728
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1