NR3C1, Mouse, Clone: 6E6, Abnova™

Mouse monoclonal antibody raised against partial recombinant NR3C1.

Supplier:  Abnova Corporation MAB10837

Catalog No. 89-109-041

Description

The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq

Specifications

• Antigen: NR3C1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Gene: NR3C1
• Gene Symbols: NR3C1
• Immunogen: Recombinant protein corresponding to human NR3C1.
• Regulatory Status: RUO
• Gene ID (Entrez): 2908
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: 6E6
• Description: Mouse monoclonal antibody raised against partial recombinant NR3C1.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: GCCR/GCR/GR/GRL
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid