NR3C1, Mouse, Clone: 6E6, Abnova™

Catalog No.	Quantity
89-109-041	100 μL

Catalog No. 89-109-041 Supplier Abnova Corporation Supplier No. MAB10837

Description

Mouse monoclonal antibody raised against partial recombinant NR3C1.

The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq

Specifications

• Antigen: NR3C1
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 6E6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant NR3C1.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: NR3C1
• Gene Alias: GCCR/GCR/GR/GRL
• Gene Symbols: NR3C1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human NR3C1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2908
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1