NRCAM, Mouse, Clone: RNL-1, Abnova™

Mouse monoclonal antibody raised against native NRCAM.

Supplier:  Abnova Corporation MAB3561

Catalog No. 89-111-470

Description

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: NRCAM
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:10-1:25) The optimal working dilution should be determined by the end user.
• Gene: NRCAM
• Gene Symbols: NRCAM
• Immunogen: Native purified NRCAM from NCI-H82 cell.
• Regulatory Status: RUO
• Gene ID (Entrez): 4897
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry (Frozen)
• Clone: RNL-1
• Description: Mouse monoclonal antibody raised against native NRCAM.
• Formulation: In cell culture supernatant (0.09% sodium azide)
• Gene Alias: KIAA0343/MGC138845/MGC138846
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with extracellular domain of the NRCAM.
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG1