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NRCAM, Mouse, Clone: RNL-1, Abnova™

Catalog No. 89111470 Shop All Abnova Corporation Products
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89-111-470 1 mL
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Catalog No. 89-111-470 Supplier Abnova Corporation Supplier No. MAB3561
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Description

Mouse monoclonal antibody raised against native NRCAM.

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

Antigen NRCAM
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Clone RNL-1
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native NRCAM.
Dilution Immunohistochemistry (1:10-1:25) The optimal working dilution should be determined by the end user.
Formulation In cell culture supernatant (0.09% sodium azide)
Gene NRCAM
Gene Alias KIAA0343/MGC138845/MGC138846
Gene Symbols NRCAM
Host Species Mouse
Immunogen Native purified NRCAM from NCI-H82 cell.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4897
Test Specificity This antibody reacts with extracellular domain of the NRCAM.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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