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NSD1, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89107275 Shop All Abnova Corporation Products
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89-107-275 50 μL
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Catalog No. 89-107-275 Supplier Abnova Corporation Supplier No. H00064324A01
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Description

Mouse polyclonal antibody raised against a partial recombinant NSD1.

This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98kDa on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq

Sequence: DQTCELPRRNCLLPFSNPVNLDAPEDKDSPFGNGQSNFSEPLNGCTMQLSTVSGTSQNAYGQDSPSCYIPLRRLQDLASMINVEYLNGSADGSESFQDPEKSDSRAQT

Specifications

Antigen NSD1
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant NSD1.
Formulation 50% glycerol
Gene NSD1
Gene Accession No. NM_022455
Gene Alias ARA267/DKFZp666C163/FLJ10684/FLJ22263/FLJ44628/KMT3B/SOTOS/STO
Gene Symbols NSD1
Host Species Mouse
Immunogen NSD1 (NP_071900, 2 a.a. ∽ 109 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64324
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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