NT5E, Mouse, Clone: 1D7, Abnova™

Catalog No.	Quantity
89-109-042	100 μL

Catalog No. 89-109-042 Supplier Abnova Corporation Supplier No. MAB10838

Description

Mouse monoclonal antibody raised against partial recombinant NT5E.

Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70kDa subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.[supplied by OMIM

Specifications

• Antigen: NT5E
• Applications: ELISA, Immunohistochemistry
• Classification: Monoclonal
• Clone: 1D7
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant NT5E.
• Dilution: ELISA (1:10000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: NT5E
• Gene Alias: CD73/E5NT/NT/NT5/NTE/eN/eNT
• Gene Symbols: NT5E
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human NT5E.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4907
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1