MilliporeSigma™ Mouse anti-NTR1, Clone: 8F11.1,

Catalog No.	Quantity
MABN350MI	100 μg

Catalog No. MABN350MI Supplier MilliporeSigma™ Supplier No. MABN350

Description

Mouse Monoclonal Antibody

Specifically detects NTR1 clone: 8F11.1 in Human, Mouse samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting

Neurotensin receptor type 1 (UniProt P30989; also known as High-affinity levocabastine-insensitive neurotensin receptor, NT-R-1, NTR1, NTRH) is encoded by the NTSR1 (also known as NTRR) gene (Gene ID 4923) in human. Neurotensin (NT) is a tridecapeptide that acts as a neuromodulator in the CNS. It also behaves as a hormone in the gastrointestinal tract. Four different NTSRs have been reported. NTSR1 and NTSR2 are seven-transmembrane G-protein-coupled receptors (GPCRs), while NTSR3 and NTSR4 are members of the sortilin protein family with a single-transmembrane spanning domain. NTSR1 is a high affinity NT receptor and plays an important role in cancer cell proliferation, survival, mobility, and invasion. NT has also been implicated in the pathophysiology of several CNS disorders, such as schizophrenia, drug abuse, eating disorders, and Parkinson’s disease.

Specifications

• Antigen: NTR1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 8F11.1
• Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: P30989
• Gene Symbols: NTSR1; NTRR
• Host Species: Mouse
• Immunogen: KLH-conjugated linear peptide corresponding to human NTR1 near the C-terminus.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Neuroscience
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_002522
• Target Species: Human, Mouse
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG1 κ

For Research Use Only