Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

MilliporeSigma™ Mouse anti-Oct-1 (Ascites Free), Clone: YL15,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MAB5434C

Catalog No. MAB5434C


Only null left
Add to Cart

Description

Description

Specifically detects Oct-1 (Ascites Free) clone: YL15 in Human, Mouse samples, and it is validated for ChIP, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting

POU domain, class 2, transcription factor 1 (UniProt P14859; also known as NF-A1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, OTF-1) is encoded by the POU2F1 (also known as OCT1, OTF1) gene (Gene ID 5451) in human. Oct-1 belongs to the family of octamer transcription factors characterized by their binding to the ATTTGCAT octamer sequence via their POU domain (a.a. 280-354 of human Oct-1). Oct1 is widely expressed in adult tissues, however, Oct-1 knockdown has little impact on cell growth and viability in culture. Oct-1 controls multiple stem cell phenotypes in normal and tumor cells. Oct-1 promotes resistance to genotoxic and oxidative stresses in stem cells. Loss of Oct-1 antagonizes oncogenic transformation in vitro and tumorigenicity in vivo.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Oct-1 (Ascites Free)
Monoclonal
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
POU2F1; OCT1; OTF1
Recombinant full-length human Oct-1.
100 μg
Epigenetics and Nuclear Function
NP_001185712
Stable for one year at 2°C to 8°C from date of receipt.
IgG1 κ
ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
YL15
P14859
Mouse
Protein G Purified
RUO
Primary
Human, Mouse
Purified
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.

For Research Use Only