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Description
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq
Specifications
Specifications
| Antigen | OLIG2 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 1G11 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant OLIG2. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | OLIG2 |
| Gene Alias | BHLHB1/OLIGO2/PRKCBP2/RACK17/bHLHe19 |
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