MilliporeSigma™ Mouse anti-Pax-2, Clone: 4C2.2,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABE902

Catalog No. MABE902MI

Description

Specifically detects Pax-2 clone: 4C2.2 in Human samples, and it is validated for Western Blotting

Paired box protein Pax-2 (UniProt Q02962; also known as Paired box homeotic gene 2) is encoded by the PAX2 (also known as FSGS7, PAPRS) gene (Gene ID 5076) in human. Pax-2 belongs to the family of transcription factors with conserved DNA-binding paired box domain. The family of paired box (PAX) genes is divided into four subgroups (I–IV). Genes in subgroups II (PAX2, PAX5, and PAX8) and III (PAX3 and PAX7) have been implicated in tumor development. PAX2 is a critical regulator of embryogenesis and it is normally expressed in the pancreas and in subpopulations of nodal lymphocytes in adult tissues. Aberrant PAX2 expression is frequently observed in several cancer types.

Specifications

• Antigen: Pax-2
• Classification: Monoclonal
• Formulation: Mouse monoclonal IgG2bκ antibody in buffer containing supernatant without preservatives.
• Gene Symbols: PAX2
• Immunogen: GST-tagged recombinant protein corresponding to human Pax-2.
• Quantity: 200 μL
• Research Discipline: Epigenetics and Nuclear Function
• Gene ID (Entrez): NP_000269
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
• Isotype: IgG2b κ

• Applications: Western Blot
• Clone: 4C2.2
• Gene Accession No.: Q02962
• Host Species: Mouse
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Form: Supernatant

For Research Use Only