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PCDHA3, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89107125 Shop All Abnova Corporation Products
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89-107-125 50 μL
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Catalog No. 89-107-125 Supplier Abnova Corporation Supplier No. H00056145A01
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Description

Mouse polyclonal antibody raised against a partial recombinant PCDHA3.

This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq

Sequence: LDVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSA

Specifications

Antigen PCDHA3
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant PCDHA3.
Formulation 50% glycerol
Gene PCDHA3
Gene Accession No. NM_018906
Gene Alias MGC141669/PCDH-ALPHA3
Gene Symbols PCDHA3
Host Species Mouse
Immunogen PCDHA3 (NP_061729, 180 a.a. ∽ 287 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56145
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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