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PCDHGA2, Mouse, Clone: 2A7, Abnova™

Catalog No. 89107109 Shop All Abnova Corporation Products
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89-107-109 200 μL
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Catalog No. 89-107-109 Supplier Abnova Corporation Supplier No. H00056113M01A
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Description

Mouse monoclonal antibody raised against a partial recombinant PCDHGA2.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq

Sequence: SGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDGPGLLTRA

Specifications

Antigen PCDHGA2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2A7
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant PCDHGA2.
Formulation ascites with no preservative
Gene PCDHGA2
Gene Accession No. NM_018915
Gene Alias PCDH-GAMMA-A2
Gene Symbols PCDHGA2
Host Species Mouse
Immunogen PCDHGA2 (NP_061738,223 a.a. ∽ 331 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56113
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Ascites
Isotype IgG2a κ
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