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PCDHGB4, Mouse, Polyclonal Antibody, Abnova™

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89-105-903 50 μL
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Catalog No. 89-105-903 Supplier Abnova Corporation Supplier No. H00008641A01
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Description

Mouse polyclonal antibody raised against a partial recombinant PCDHGB4.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq

Sequence: STAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGG

Specifications

Antigen PCDHGB4
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant PCDHGB4.
Formulation 50% glycerol
Gene PCDHGB4
Gene Accession No. NM_003736
Gene Alias CDH20/FIB2/MGC138293/MGC142167/PCDH-GAMMA-B4
Gene Symbols PCDHGB4
Host Species Mouse
Immunogen PCDHGB4 (NP_003727, 224 a.a. ∽ 323 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8641
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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