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PCDHGB5, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a partial recombinant PCDHGB5.
Supplier: Abnova Corporation H00056101A01
Description
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq
Sequence: RTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGSpecifications
PCDHGB5 | |
Polyclonal | |
Mouse polyclonal antibody raised against a partial recombinant PCDHGB5. | |
PCDHGB5 | |
PCDH-GAMMA-B5 | |
Mouse | |
50 μL | |
Primary | |
Human | |
Antisera |
ELISA, Western Blot | |
Unconjugated | |
50% glycerol | |
NM_018925 | |
PCDHGB5 | |
PCDHGB5 (NP_061748, 283 a.a. ∽ 373 a.a) partial recombinant protein with GST tag. | |
RUO | |
56101 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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For Research Use Only