PCNA, Mouse, Clone: IML-83, Abnova™

Catalog No.	Quantity
89-110-473	100 μg

Catalog No. 89-110-473 Supplier Abnova Corporation Supplier No. MAB1524

Description

Mouse monoclonal antibody raised against native PCNA.

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq

Specifications

• Antigen: PCNA
• Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: PC 10
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native PCNA.
• Dilution: Western Blot (2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.4-1 ug/mL) Immunohistochemistry (Frozen sections) (0.4-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)
• Gene: PCNA
• Gene Alias: MGC8367
• Gene Symbols: PCNA
• Host Species: Mouse
• Immunogen: Native purified human PCNA.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5111
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG2a