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Description
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq
Specifications
Specifications
| Antigen | PCNA |
| Applications | ELISA |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant PCNA. |
| Formulation | 50% glycerol |
| Gene | PCNA |
| Gene Accession No. | NM_002592 |
| Gene Alias | MGC8367 |
| Gene Symbols | PCNA |
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