PCSK9, Mouse, Clone: KS-2C8, Abnova™

Catalog No.	Quantity
89-113-393	100 μg

Catalog No. 89-113-393 Supplier Abnova Corporation Supplier No. MAB8228

Description

Mouse monoclonal antibody raised against full-length recombinant PCSK9.

This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq

Specifications

• Antigen: PCSK9
• Applications: Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: KS-2C8
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant PCSK9.
• Dilution: Western Blot (0.5-1 ug/mL) Immunoprecipitation (1-2 ug/sample) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM phosphate buffer, 150mM NaCl, pH 7.5 (50% glycerol)
• Gene: PCSK9
• Gene Alias: FH3/HCHOLA3/LDLCQ1/NARC-1/NARC1
• Gene Symbols: PCSK9
• Host Species: Mouse
• Immunogen: Recombinant His fusion protein corresponding to full length human PCSK9.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 255738
• Test Specificity: This antibody detects endogenous mature form of PCSK9 prodomain, does not react with pro-form of PCSK9.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1