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PDGFRA, Mouse, Clone: 16A1, Abnova™

Catalog No. 89113479 Shop All Abnova Corporation Products
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89-113-479 100 μg
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Catalog No. 89-113-479 Supplier Abnova Corporation Supplier No. MAB8511
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Description

Mouse monoclonal antibody raised against PDGFRA.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq

Specifications

Antigen PDGFRA
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone 16A1
Concentration 1 mg/mL
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against PDGFRA.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.09% sodium azide)
Gene PDGFRA
Gene Alias CD140A/MGC74795/PDGFR2/Rhe-PDGFRA
Gene Symbols PDGFRA
Host Species Mouse
Immunogen Human PDGFRA transfected NIH/3T3 cells.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5156
Test Specificity This antibody is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in various tumours.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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