PDGFRB, Mouse, Clone: 18A2, Abnova™

Catalog No.	Quantity
89-113-476	100 μg

Catalog No. 89-113-476 Supplier Abnova Corporation Supplier No. MAB8507

Description

Mouse monoclonal antibody raised against full-length recombinant PDGFRB.

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq

Specifications

• Antigen: PDGFRB
• Applications: Flow Cytometry, Immunocytochemistry
• Classification: Monoclonal
• Clone: 18A2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant PDGFRB.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: PDGFRB
• Gene Alias: CD140B/JTK12/PDGF-R-beta/PDGFR/PDGFR1
• Gene Symbols: PDGFRB
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human PDGFRB.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5159
• Test Specificity: This antibody is specific to PDGFRB.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1