MilliporeSigma™ Mouse anti-PELP1, Clone: 2F11.1,

Catalog No.	Quantity
MABC303MI	100 μg

Catalog No. MABC303MI Supplier MilliporeSigma™ Supplier No. MABC303

Description

Mouse Monoclonal Antibody

Specifically detects PELP1 clone: 2F11.1 in Human samples, and it is validated for Immunocytochemistry, Western Blotting

Proline-, glutamic acid- and leucine-rich protein 1 (UniProt Q8IZL8; also known as Modulator of non-genomic activity of estrogen receptor, p160, Proline and glutamic acid rich nuclear protein,Transcription factor HMX3) is encoded by the PELP1 (Also known as HMX3, MNAR, P160) gene in human (Gene ID 27043). PELP1 functions as scaffolding protein and mediates protein–protein interactions in cellular processes involving both genomic and extranuclear signaling pathways. Multiple structural domains allow PELP1 to interact with various steroid receptors (SRs) to modulate their activity as either corepressor or coactivator. Dysregulation of PELP1 expression has been observed in breast, ovarian, endometrial, brain, and prostate cancers.

Specifications

• Antigen: PELP1
• Applications: Immunocytochemistry, Western Blot
• Classification: Monoclonal
• Clone: 2F11.1
• Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: Q8IZL8
• Gene Symbols: PELP1; HMX3; MNAR
• Host Species: Mouse
• Immunogen: GST-tagged recombinant protein corresponding to human PELP1.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Apoptosis, Cancer
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_001265170
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG2a κ

For Research Use Only