MilliporeSigma™ Mouse anti-Pex3, Clone: 14F3.2,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABC550

Catalog No. MABC550MI

Description

Specifically detects Pex3 clone: 14F3.2 in Human samples, and it is validated for Immunohistochemistry, Western Blotting

Pex3 (also known as peroxin-3, peroxisomal assembly protein PEX3, peroxisomal biogenesis factor 3, transformation-related protein 18) is a multitransmembrane peroxisome protein that is encoded by the PEX3 gene in human (also known as PBD10A and TRG18). Pex19 is involved in maintaining peroxisome biosynthesis and integrity by acting as a docking factor for pex19 and, together with other peroxins (PEXs), is essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs), including Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP), are lethal diseases characterized by multiple defects in peroxisome function, resulting in failure of importing one or more classes of peroxisomal matrix proteins into the organelle.

Specifications

• Antigen: Pex3
• Classification: Monoclonal
• Formulation: Purified mouse monoclonal IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: PEX3
• Immunogen: GST-tagged recombinant protein corresponding to human Pex3.
• Quantity: 100 μg
• Research Discipline: Apoptosis, Cancer
• Gene ID (Entrez): NP_003621
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG2b κ

• Applications: Immunohistochemistry, Western Blot
• Clone: 14F3.2
• Gene Accession No.: P56589
• Host Species: Mouse
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

For Research Use Only