PGR, Mouse, Clone: 608, Abnova™

Catalog No.	Quantity
89-110-628	100 μL

Catalog No. 89-110-628 Supplier Abnova Corporation Supplier No. MAB1786

Description

Mouse monoclonal antibody raised against synthetic phosphopeptide of PGR.

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq

Specifications

• Antigen: PGR
• Applications: Immunohistochemistry (Frozen), Western Blot
• Classification: Monoclonal
• Clone: 608
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic phosphopeptide of PGR.
• Dilution: Immunohistochemistry (Frozen sections) (1:1000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM HEPES, 150mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
• Gene: PGR
• Gene Alias: NR3C3/PR
• Gene Symbols: PGR
• Host Species: Mouse
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S294 of human PGR.
• Purification Method: Protein G purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5241
• Test Specificity: This antibody recognizes ∼90KDa PR-A isoform and the ∼120 KDa PR-B isoform.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1