PKLR, Mouse, Clone: AT1E3, Abnova™

Catalog No.	Quantity
89-109-300	100 μL

Catalog No. 89-109-300 Supplier Abnova Corporation Supplier No. MAB11108

Description

Mouse monoclonal antibody raised against partial recombinant PKLR.

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: PKLR
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: AT1E3
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant PKLR.
• Dilution: Western Blot (1:500) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: PKLR
• Gene Alias: PK1/PKL/PKR/PKRL/RPK
• Gene Symbols: PKLR
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 47-574 of human PKLR.
• Purification Method: Protein G purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5313
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ