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Mouse anti-Plasma Cell, Clone: LIV3G11 (7B18), Novus Biologicals™
SDP

Catalog No. NBP22523902 Shop All R&D Systems Products
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0.2 mg
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NBP22523902 0.2 mg
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Catalog No. NBP22523902 Supplier Novus Biologicals Supplier No. NBP2252390.2MG

Specifications

Antigen Plasma Cell
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone LIV3G11 (7B18)
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 0.5-1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Alias Plasma
Host Species Mouse
Immunogen Pancreatic cancer related serum mucin was used as the immunogen for the Plasma Cell antibody.
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
Reconstitution Protein A purified
Target Species Human, Rat (Negative)
Content And Storage Store at 4C.
Form Purified
Isotype IgG2a
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