PLAT, Mouse, Clone: 629-2A153, Abnova™

Catalog No.	Quantity
89-111-595	1 mg

Catalog No. 89-111-595 Supplier Abnova Corporation Supplier No. MAB3792

Description

Mouse monoclonal antibody raised against recombinant PLAT.

This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: PLAT
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 629-2A153
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant PLAT.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In 50mM sodium phosphate buffer, 1mM NaCl, pH 6.6
• Gene: PLAT
• Gene Alias: DKFZp686I03148/T-PA/TPA
• Gene Symbols: PLAT
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human PLAT.
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5327
• Test Specificity: This epitope is localized to the heavy chain of human tPA and binds well to both the free and complexed form.
• Target Species: Human
• Content And Storage: Store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG