PLAUR, Mouse, Clone: 2F11, Abnova™

Catalog No.	Quantity
89-105-138	100 μg

Catalog No. 89-105-138 Supplier Abnova Corporation Supplier No. H00005329M01

Description

Mouse monoclonal antibody raised against a partial recombinant PLAUR.

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq

Sequence: CMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEPELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQS

Specifications

• Antigen: PLAUR
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 2F11
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant PLAUR.
• Formulation: PBS with no preservative; pH 7.2
• Gene: PLAUR
• Gene Accession No.: NM_002659
• Gene Alias: CD87/UPAR/URKR
• Gene Symbols: PLAUR
• Host Species: Mouse
• Immunogen: PLAUR (NP_002650,25 a.a. ∽ 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Protein A Purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5329
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Purified
• Isotype: IgG1 κ