PLCG1, Mouse, Clone: M156, Abnova™

Catalog No.	Quantity
89-110-393	100 μL

Catalog No. 89-110-393 Supplier Abnova Corporation Supplier No. MAB1377

Description

Mouse monoclonal antibody raised against synthetic peptide of PLCG1.

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: PLCG1
• Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: M156
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of PLCG1.
• Dilution: ELISA (1:2000) Immunocytochemistry (1:100) Immunoprecipitation (1-5 ul) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene: PLCG1
• Gene Alias: PLC-II/PLC1/PLC148/PLCgamma1
• Gene Symbols: PLCG1
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to N-terminus of human PLCG1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5335
• Test Specificity: This sequence is highly conserved in rat and mouse PLCg1, and has low homology to PLCg2.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1