PMS2, Mouse, Clone: 349.29.5.2, Abnova™

Catalog No.	Quantity
89-110-816	100 μg

Catalog No. 89-110-816 Supplier Abnova Corporation Supplier No. MAB2089

Description

Mouse monoclonal antibody raised against partial recombinant PMS2.

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq

Specifications

• Antigen: PMS2
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 1204
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant PMS2.
• Dilution: ELISA (1:5000-1:20000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene: PMS2
• Gene Alias: HNPCC4/PMS2CL/PMSL2
• Gene Symbols: PMS2
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to the first 133 amino acids of human PMS2.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5395
• Test Specificity: This is an protein A purified antibody directed against PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2.
• Target Species: Chimpanzee, Human, Mouse, Rat
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ