Learn More
Description
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq]
Specifications
Specifications
| Antigen | PNPO |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | AT2C7 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant PNPO. |
| Dilution | Western Blot (1:500-1:5000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.09% sodium azide) |
| Gene | PNPO |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.