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POLR2A, Mouse, Clone: 8A7, Abnova™

Catalog No. 89111007 Shop All Abnova Corporation Products
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89-111-007 50 μL
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Catalog No. 89-111-007 Supplier Abnova Corporation Supplier No. MAB2441

Mouse monoclonal antibody raised against synthetic phosphopeptide of POLR2A.

This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq

Sequence: YSPTSPS

Specifications

Antigen POLR2A
Applications ELISA, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 8A7
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against synthetic phosphopeptide of POLR2A.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene POLR2A
Gene Alias MGC75453/POLR2/POLRA/RPB1/RPBh1/RPO2/RPOL2/RpIILS/hRPB220/hsRPB1
Gene Symbols POLR2A
Host Species Mouse
Immunogen Synthetic phosphopeptide corresponding to residues surrounding S5 of human POLR2A.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5430
Test Specificity recognizes the phosphorylated (Ser5) form of POLR2A in human and S. cerevisiae.
Target Species Human, Yeast
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgM
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