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Description
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Specifications
Specifications
| Antigen | PPOX |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 2B5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant PPOX. |
| Formulation | ascites with no preservative |
| Gene | PPOX |
| Gene Accession No. | BC002357 |
| Gene Alias | MGC8485/PPO/V290M/VP |
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