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Description
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | PRDM2 |
| Applications | ELISA, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 33AT1045 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant PRDM2. |
| Dilution | Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | PRDM2 |
| Gene Accession No. | NM_012231;NM_01586 |
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