PRKACA, Mouse, Clone: 6D2.1, Abnova™

Catalog No.	Quantity
89-111-491	100 μg

Catalog No. 89-111-491 Supplier Abnova Corporation Supplier No. MAB3591

Description

Mouse monoclonal antibody raised against synthetic peptide of PRKACA.

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq

Sequence: ESPAQNTAHLDQFERIK

Specifications

• Antigen: PRKACA
• Applications: Dot Blot, Western Blot
• Classification: Monoclonal
• Clone: 6D2.1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of PRKACA.
• Dilution: Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: PRKACA
• Gene Alias: MGC102831/MGC48865/PKACA
• Gene Symbols: PRKACA
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to human PRKACA.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5566
• Test Specificity: This antibody strongly reacts with human proteinkinase A catalytic (PRKACA) alpha subunit, and weakly with PKAc gamma subunit (both around 40 KDa). The recognized epitope of PKAc alpha is identical between man, sheep, pig, ox and dog.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG