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Description
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. [provided by RefSeq
Specifications
Specifications
| Antigen | PTK6 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 2H12B8 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant PTK6. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | PTK6 |
| Gene Alias | BRK/FLJ42088 |
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