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Description
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | PTK7 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 4F9 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant PTK7. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | PTK7 |
| Gene Alias | CCK4 |
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