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PTPN6, Mouse, Clone: M160, Abnova™

Catalog No. 89110395 Shop All Abnova Corporation Products
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89-110-395 100 μL
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Catalog No. 89-110-395 Supplier Abnova Corporation Supplier No. MAB1379
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Description

Mouse monoclonal antibody raised against partial recombinant PTPN6.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq

Specifications

Antigen PTPN6
Applications ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone M160
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant PTPN6.
Dilution ELISA (1:2000) Immunocytochemistry (1:100) Immunoprecipitation (5-10 ul) Western Blot (1:500) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
Gene PTPN6
Gene Alias HCP/HCPH/HPTP1C/PTP-1C/SH-PTP1/SHP-1/SHP-1L/SHP1
Gene Symbols PTPN6
Host Species Mouse
Immunogen Recombinant protein corresponding to C-terminus of human PTPN6.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5777
Test Specificity This sequence is highly conserved in rat and mouse SHP1.
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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