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PTPN6, Mouse, Clone: PTY15, Abnova™

Catalog No. 89112857 Shop All Abnova Corporation Products
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500 μg
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89-112-857 500 μg
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Catalog No. 89-112-857 Supplier Abnova Corporation Supplier No. MAB6402
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Description

Mouse monoclonal antibody raised against full-length recombinant PTPN6.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq

Specifications

Antigen PTPN6
Applications ELISA, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone PTY15
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length recombinant PTPN6.
Dilution The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 10mM PBS, pH 7.2
Gene PTPN6
Gene Alias HCP/HCPH/HPTP1C/PTP-1C/SH-PTP1/SHP-1/SHP-1L/SHP1
Gene Symbols PTPN6
Host Species Mouse
Immunogen Recombinant protein corresponding to full length human PTPN6.
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5777
Test Specificity This antibody recognizes single 67 KDa PTPN6 in human cells that express the enzyme and the SH2(C) domain.
Target Species Human
Content And Storage Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG1 κ
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