Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 89110815

PTPRC, Mouse, Clone: SPM54, Abnova™

Catalog No. 89110815 Shop All Abnova Corporation Products
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
89-110-815 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 89-110-815 Supplier Abnova Corporation Supplier No. MAB2084

Description

Mouse monoclonal antibody raised against native PTPRC.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq

Specifications

Antigen PTPRC
Applications Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone SPM504
Concentration Lot specific
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native PTPRC.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene PTPRC
Gene Alias B220/CD45/CD45R/GP180/LCA/LY5/T200
Gene Symbols PTPRC
Host Species Mouse
Immunogen Native purified PTPRC from stimulated human leucocytes.
Purification Method Protein A purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5788
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.