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MilliporeSigma™ Mouse anti-Rad51, Clone: 3C10,

Catalog No. 05530IMI Shop All MilliporeSigma Products
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05-530-IMI 200 μg
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Description

Mouse Monoclonal Antibody

Specifically detects Rad51 clone: 3C10 in Human samples, and it is validated for Immunoprecipitation, Western Blotting

DNA repair protein RAD51 homolog 1 (UniProt Q06609; also known as BRCA1/BRCA2-containing complex subunit 5, Homolog of E. coli RecA, hRAD51, HsRAD51, RAD51 homolog A, RecA-like protein, Recombination protein A) is encoded by the RAD51 (also known as HRAD51, HsT16930, BRCC5, MRMV2, RAD51A, RECA) gene (Gene ID 5888) in human. RAD51 is a member of the RecA family recombinases. It interacts with BRCA1 and BRCA2 to activate homologous recombination. RAD51 exhibits DNA-dependent ATPase activity and participates in double-strand break (DSB) repair by unwinding DNA to form a helical nucleoprotein filament. It is highly expressed in the testis and thymus and lower expression levels are found in the small intestine, placenta, colon, pancreas, and ovaries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Rad51
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 3C10
Formulation Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. Q06609
Gene Symbols RAD51; RAD51A; RECA
Host Species Mouse
Immunogen Recombinant protein corresponding to human Rad51.
Purification Method Protein G Purified
Quantity 200 μg
Regulatory Status RUO
Research Discipline Epigenetics and Nuclear Function
Primary or Secondary Primary
Gene ID (Entrez) NP_002866
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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