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RAD51C, Mouse, Clone: 2H11/6, Abnova™

Catalog No. 89110982 Shop All Abnova Corporation Products
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89-110-982 100 μL
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Catalog No. 89-110-982 Supplier Abnova Corporation Supplier No. MAB2387
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Description

Mouse monoclonal antibody raised against recombinant RAD51C.

This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq

Specifications

Antigen RAD51C
Applications Western Blot
Classification Monoclonal
Clone 2H11/6
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant RAD51C.
Dilution Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.02% sodium azide)
Gene RAD51C
Gene Alias MGC104277/RAD51L2
Gene Symbols RAD51C
Host Species Mouse
Immunogen Recombinant His fusion protein corresponding to human RAD51C.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5889
Test Specificity This antibody is specific to Rad51C.
Target Species Human, Mouse
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1 κ
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