RASSF1, Mouse, Clone: 3F3, Abnova™

Catalog No.	Quantity
89-108-750	100 μL

Catalog No. 89-108-750 Supplier Abnova Corporation Supplier No. MAB1056

Description

Mouse monoclonal antibody raised against full-length recombinant RASSF1.

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq

Specifications

• Antigen: RASSF1
• Applications: ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 3F3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant RASSF1.
• Dilution: Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: RASSF1
• Gene Alias: 123F2/NORE2A/RASSF1A/RDA32/REH3P21
• Gene Symbols: RASSF1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human RASSF1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11186
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ