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CD45 Mouse anti-Rat, Brilliant Violet 786, Clone: OX-1, BD Optibuild™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 740914

Catalog No. BDB740914


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Description

Description

The OX-1 antibody recognizes all molecular forms of CD45 (Leukocyte Common Antigen) on all hematopoietic cells except erythrocytes. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family; its intracellular (COOH-terminal) region contains two PTP catalytic domains while the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), and differing levels of glycosylation. The CD45 isoforms detected in rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD45
Monoclonal
0.2mg/mL
Ptprc; Lca; Leucocyte common antigen; RT7; T200
Mouse
Affinity Purified
RUO
Rat
IgG1 κ
Flow Cytometry
OX-1
Brilliant Violet 786
Aqueous buffered solution containing ≤0.09% sodium azide.
Leukocyte Common Antigen-enriched Glycoprotein Fraction from Wistar Rat Thymocytes
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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