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RB1, Mouse, Clone: 1G5, Abnova™

Catalog No. 89110862 Shop All Abnova Corporation Products
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89-110-862 100 μg
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Catalog No. 89-110-862 Supplier Abnova Corporation Supplier No. MAB2166
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Description

Mouse monoclonal antibody raised against partial recombinant RB1.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Specifications

Antigen RB1
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 1G5
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant RB1.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4
Gene RB1
Gene Alias OSRC/RB/p105-Rb/pRb/pp110
Gene Symbols RB1
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 371-390 of RB1.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Test Specificity This antibody recognizes an epitope within aa 371-390 of RB1.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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