RB1, Mouse, Clone: 3C8, Abnova™

Mouse monoclonal antibody raised against partial recombinant RB1.

Supplier:  Abnova Corporation MAB2169

Catalog No. 89-110-865

Description

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Specifications

• Antigen: RB1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: RB1
• Gene Symbols: RB1
• Immunogen: Recombinant protein corresponding to amino acids 886-905 of RB1.
• Regulatory Status: RUO
• Gene ID (Entrez): 5925
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Clone: 3C8
• Description: Mouse monoclonal antibody raised against partial recombinant RB1.
• Formulation: In PBS, pH 7.4
• Gene Alias: OSRC/RB/p105-Rb/pRb/pp110
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes an epitope within aa 886-905 of RB1.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2a