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RB1, Mouse, Clone: 7E4B8, Abnova™

Catalog No. 89108571 Shop All Abnova Corporation Products
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89-108-571 100 μL
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Catalog No. 89-108-571 Supplier Abnova Corporation Supplier No. MAB10384
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Description

Mouse monoclonal antibody raised against recombinant RB1.

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq

Specifications

Antigen RB1
Applications ELISA, Immunohistochemistry
Classification Monoclonal
Clone 7E4B8
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant RB1.
Dilution ELISA (1:10000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.
Formulation In ascites (0.03% sodium azide)
Gene RB1
Gene Alias OSRC/RB/p105-Rb/pRb/pp110
Gene Symbols RB1
Host Species Mouse
Immunogen Recombinant protein corresponding to human RB1.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5925
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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