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Description
The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | RCHY1 |
| Applications | ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 1H10 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant RCHY1. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | RCHY1 |
| Gene Alias | ARNIP/CHIMP/DKFZp586C1620/PIRH2/PRO1996/RNF199/ZNF363/hARNIP |
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