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Description
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM
Specifications
Specifications
| Antigen | REL |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 1E7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant REL. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | REL |
| Gene Alias | C-Rel |
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