REN, Mouse, Clone: 244/OE6, Abnova™

Mouse monoclonal antibody raised against recombinant REN.

Supplier:  Abnova Corporation MAB3695

Catalog No. 89-111-542

Description

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq

Specifications

• Antigen: REN
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: REN
• Gene Symbols: REN
• Immunogen: Recombinant protein corresponding to human REN.
• Regulatory Status: RUO
• Gene ID (Entrez): 5972
• Target Species: Human
• Form: Liquid

• Applications: ELISA
• Clone: 244/OE6
• Description: Mouse monoclonal antibody raised against recombinant REN.
• Formulation: In BBS
• Gene Alias: FLJ10761
• Host Species: Mouse
• Quantity: 1 mg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes prorenin and active renin.
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ