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REN, Mouse, Clone: 244/OE6, Abnova™

Catalog No. 89111542 Shop All Abnova Corporation Products
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89-111-542 1 mg
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Catalog No. 89-111-542 Supplier Abnova Corporation Supplier No. MAB3695
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Description

Mouse monoclonal antibody raised against recombinant REN.

Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq

Specifications

Antigen REN
Applications ELISA
Classification Monoclonal
Clone 244/OE6
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant REN.
Dilution The optimal working dilution should be determined by the end user.
Formulation In BBS
Gene REN
Gene Alias FLJ10761
Gene Symbols REN
Host Species Mouse
Immunogen Recombinant protein corresponding to human REN.
Quantity 1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5972
Test Specificity This antibody recognizes prorenin and active renin.
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1 κ
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